15 Uplifting Bible Verses about Depression

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Depression is a deep emotional struggle that affects millions of people around the world. In times of darkness, finding peace and hope can be challenging, but the Bible offers us a source of comfort and encouragement. In this blog post, I want to share with you 15 inspiring Bible verses that have brought light and hope to my own journey through depression. May you be filled with the strength, comfort, and renewed faith you need to overcome the depths of despair.

Are you feeling anxious and empty? I’d love to share a powerful story with you to give you a fresh sense of comfort and hope. Click here if you’re ready to let go and let God have control!

We have included a short prayer for you at the end of the post! God bless!

1. Philippians 4:6-7

“Don’t worry about anything; instead, pray about everything. Tell God what you need, and thank him for all he has done. Then you will experience God’s peace, which exceeds anything we can understand. His peace will guard your hearts and minds as you live in Christ Jesus.”

Paul encourages us to surrender our worries and anxieties to God through prayer. As we express our needs and offer gratitude for His faithfulness, we are enveloped by His surpassing peace—a peace that transcends human understanding and guards our hearts and minds in Christ.

2. Psalm 34:17-18

“The LORD hears his people when they call to him for help. He rescues them from all their troubles. The LORD is close to the brokenhearted; he rescues those whose spirits are crushed.”

In our moments of despair, God hears our cries for help. He is near to those who are brokenhearted and lifts up the spirits of those who feel crushed. We can find peace and hope in His presence and trust in His deliverance.

3. Psalm 42:11

“Why am I discouraged? Why is my heart so sad? I will put my hope in God! I will praise him again—my Savior and my God!”

This verse acknowledges the feelings of discouragement and sadness but encourages us to put our hope in God. When we turn to Him in praise and trust, He becomes our source of strength and salvation.

4. Isaiah 41:10

“Don’t be afraid, for I am with you. Don’t be discouraged, for I am your God. I will strengthen you and help you. I will hold you up with my victorious right hand.”

God assures us of His presence and support in our times of fear and discouragement. He promises to strengthen us, help us, and hold us up with His victorious hand. We can find courage and renewed hope in His unfailing love.

5. Psalm 55:22

“Give your burdens to the LORD, and he will take care of you. He will not permit the godly to slip and fall.”

When depression weighs us down, we can find relief by surrendering our burdens to the Lord. He promises to care for us and protect us, ensuring that we will not stumble and fall.

6. 1 Peter 5:7

“Give all your worries and cares to God, for he cares about you.”

Peter reminds us to cast all our worries and cares upon God because He genuinely cares for us. By entrusting our burdens to Him, we find comfort and reassurance in His love.

7. Matthew 11:28

“Then Jesus said, ‘Come to me, all of you who are weary and carry heavy burdens, and I will give you rest.'”

Jesus extends a compassionate invitation to those who are weary and burdened, offering rest and relief. In Him, we find hope, peace, and restoration for our weary souls.

8. Psalm 147:3

“He heals the brokenhearted and bandages their wounds.”

God is not only aware of our brokenness, but He also brings healing to our wounded hearts. His love binds up our wounds, bringing comfort and restoration.

9. Isaiah 40:31

“But those who trust in the LORD will find new strength. They will soar high on wings like eagles. They will run and not grow weary. They will walk and not faint.”

I want to encourage you to trust in God. It renews our strength, allowing us to rise above the challenges of depression. As we lean on Him, we discover resilience and endurance, enabling us to keep moving forward.

10. Romans 15:13

“I pray that God, the source of hope, will fill you completely with joy and peace because you trust in him. Then you will overflow with confident hope through the power of the Holy Spirit.”

This verse highlights the role of God as the source of hope. When we trust in Him, He fills us with joy, peace, and confident hope through the power of the Holy Spirit. Our spirits are lifted, and depression loses its grip on our hearts.

11. Psalm 30:5

“For his anger lasts only a moment, but his favor lasts a lifetime! Weeping may last through the night, but joy comes with the morning.”

In times of darkness and despair, it’s crucial to remember that God’s favor and love endure forever. Though we may experience tears and sorrow for a time, joy will eventually break through like the dawn of a new day.

If you want to start or restart your walk with Godclick here to pray a simple prayer we have set up for you.

12. 2 Corinthians 1:3-4

“All praise to God, the Father of our Lord Jesus Christ. God is our merciful Father and the source of all comfort. He comforts us in all our troubles so that we can comfort others. When they are troubled, we will be able to give them the same comfort God has given us.”

God, our merciful Father, offers us comfort and solace in our times of trouble. As we experience His comforting presence, we are equipped to extend the same compassion and support to others who may be going through similar struggles.

You can know Jesus’ love and compassion for you by clicking here.

13. Psalm 42:5

“Why am I discouraged? Why is my heart so sad? I will put my hope in God! I will praise him again—my Savior and my God!”

This verse serves as a reminder that, even in the depths of depression, we can choose to put our hope in God. By praising Him, we shift our focus from our circumstances to the faithfulness and goodness of our Savior.

14. 2 Timothy 1:7

“For God has not given us a spirit of fear and timidity, but of power, love, and self-discipline.”

God does not desire for us to live in fear and timidity, including the grip of depression. Instead, He equips us with His Spirit of power, love, and self-discipline to overcome and find freedom from our struggles.

15. Psalm 40:1-3

“I waited patiently for the LORD to help me, and he turned to me and heard my cry. He lifted me out of the pit of despair, out of the mud and the mire. He set my feet on solid ground and steadied me as I walked along. He has given me a new song to sing, a hymn of praise to our God.”

When we cry out to the Lord, He hears us and lifts us out of the depths of despair. He provides stability, grounds us in His truth, and fills our hearts with a new song of praise and gratitude.

Prayer if You’re Feeling Depressed

Dear Heavenly Father, I come before You with a heavy heart, burdened by the weight of depression. I ask that You grant me the strength to persevere and find hope in Your promises. Fill me with Your peace that surpasses all understanding, and guide me on the path of healing and restoration. Help me to trust in Your unfailing love and to lean on You for comfort and support. In Jesus’s name, I pray. Amen.

There is ultimate peace and joy in Jesus.

You see, because of sin, we fall short of God. That’s why He sent His only Son, Jesus, to die on the cross to pay the ULTIMATE price for our sins. Because of Jesus, we can be forgiven and come into a relationship with God.

This is where true peace is found – salvation in Jesus.

If you want to start or restart your walk with Godclick here to pray a simple prayer we have set up for you.


Depression may cast a dark shadow over our lives, but through faith in God and the power of His Word, we can find hope, strength, and renewed joy. May these Bible verses be a beacon of light and give you a fresh sense of God’s peace. Remember, you are not alone, and there is always hope in God’s unfailing love. Lean on Him, seek support from loved ones, and trust in His promises. With time, perseverance, and the grace of God, you can overcome the grip of depression and find new beginnings filled with peace and joy.

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